The BARRIER Bioactive Treatment
The BARRIER Bioactive Treatment
The BARRIER Bioactive Treatment
The BARRIER Bioactive Treatment
The BARRIER Bioactive Treatment
The BARRIER Bioactive Treatment
The BARRIER Bioactive Treatment
The BARRIER Bioactive Treatment
The BARRIER Bioactive Treatment
The BARRIER Bioactive Treatment

The BARRIER Bioactive Treatment

50ml  | 


 ( $158.40 Subscription)

Inspired by the immortal jellyfish, this highly concentrated, restorative overnight treatment uses bioactive marine ingredients to optimize normal skin renewal for visibly softer, stronger skin with boosted barrier function to reveal refreshed, supple-looking skin.
Inspired by the immortal jellyfish, this highly concentrated, restorative overnight treatment uses bioactive marine ingredients to optimize normal skin renewal for visibly softer, stronger skin with boosted barrier function to reveal refreshed, supple-looking skin.


Improved moisture barrier function
Boost skin renewal
Rough + dull skin
Sensitive + reactive skin

Key Ingredients

  • Urea
  • Vitamin B6
  • Sodium DNA
  • Shea Butter
  • Hyaluronic Acid
  • Purified Oat Extract
  • Fruit Hydroxy Acids
  • Jojoba Wax
  • Sunflower Wax
  • Mimosa Wax


Is the formula meant to be rinsed off?
No. With a plush gel-cream texture, it's designed as an overnight treatment that you leave on until you wake up in the morning, and then just go about your normal skincare routine.
Can I wear makeup on top of The BARRIER?
For best results, use The BARRIER at night and don’t add anything, including face makeup, on top of it. But you can: simply allow it to dry before applying subsequent layers.
Is the formula vegan?
It contains marine ingredients upcycled from fish farms. While it’s not vegan, no animals are harmed in formulating The BARRIER.
Can I use The BARRIER every single night?
Yes! You should use it at least 2-3 nights a week to see results, but you can use it as frequently as you want to wake up to baby-soft skin every morning.
How long will the product last me?
Depending how generously (and frequently) you apply it, it should last between four and six weeks.
Can I use a discount code on a subscription?
Subscriptions are already offered at a discounted price and are not eligible for additional discounts. If you have reward points, you can use them on a new subscription, or on the upcoming recurring order of your existing subscription. If you're purchasing a subscription for the first time, just proceed to the checkout page where you will be able to decide how many points you would like to redeem. If you're an active subscriber and would like to apply your points to a future shipment, go to "My Account > Redeem Points on Subscriptions". You will be able to select how many points you want to redeem and apply them on your next subscription upcoming shipment.

The BARRIER Bioactive Treatment

  • How to Use
  • Clinicals
  • Ingredients
Apply a generous layer as the last step in your evening routine. Use at least 2–3 nights a week or as needed.

Need advice on building your routine? Text one of our in-house experts to get personalized recommendations.
  • How to Use
  • Clinicals
  • Ingredients
  • 148%increase in the optimization of skin’s own natural elastin*
  • 159%increase in the optimization of skin’s own natural collagen*
  • 100%of volunteers agreed skin firmness looked improved after daily use.**
  • 93%of volunteers agreed skin looked smoother and younger after daily use.**

*In-vitro clinical study
**Consumer Perception Study with 30-Volunteers after 30 days of use

  • How to Use
  • Clinicals
  • Ingredients
Aqua (Water), Urea, Butyrospermum Parkii (Shea Butter), Butylene Glycol, Octyldodecanol, Cetearyl Ethylhexanoate, Glycerin, Isododecane, Pentylene Glycol, Methyldihydrojasmonate, Polymethyl Methacrylate, Vaccinium Myrtillus Fruit Extract, Avena Sativa (Oat) Kernel Extract, Saccharum Officinarum (Sugar Cane) Extract, Citrus Aurantium Dulcis (Orange) Fruit Extract, Citrus Limon (Lemon) Fruit Extract, Acer Saccharum (Sugar Maple) Extract, Laminaria Saccharina Extract, Macrocystis Pyrifera Extract, Tocopherol, Ascorbyl Palmitate, Salicylic Acid, Alpha-glucan Oligosaccharide, Beta-glucan, Sodium Ascorbyl Phosphate, Linoleic Acid, Oleic Acid, Palmitic Acid, Acacia Decurrens/jojoba/sunflower Seed Wax/polyglyceryl-3 Esters, Stearic Acid, Glutathione, Lactobionic Acid, Superoxide Dismutase, Hydrolyzed Hyaluronic Acid, Glycolic Acid, Sodium Hyaluronate, Mandelic Acid, Linolenic Acid, Hydrolyzed Yeast Extract, Arginine, N-prolyl Palmitoyl Tripeptide-56 Acetate, Octyldodecyl Xyloside, Peg-30 Dipolyhydroxystearate, Isopropyl Myristate, Sodium Dna, Hydroxyphenyl Propamidobenzoic Acid, Pyridoxine Hcl, Caprylyl Glycol, Xylose, Polysorbate 20, Xanthan Gum, Sodium Hydroxide, Disodium Edta, Sodium Benzoate, Potassium Sorbate

A streamlined routine

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SIREN Capsule Technology

Featuring a SIREN formulated with functional, bioactive marine ingredients engineered to act on the skin’s stem cells and essential growth factors to boost the proliferation of new cells, The BARRIER works with our SIREN Capsule Technology in two unique key ways.

First, it strategically targets damaged areas to remove them, while leaving the healthy skin barrier alone. This enables faster action and results, as the damaged barrier is renewed. Simultaneously, this patent-pending technology helps create a strategic formula that accelerates the delivery of messenger molecules to the skin’s own stem cells to renew the barrier with visibly improved and strengthened integrity.

Clinical results

Before + After

Supported barrier function
Visibly renewed skin
Optimized natural collagen expression
Visibly smoother skin

Featuring an engineered cocktail of actives, The BARRIER acts to detoxify your skin where it needs it most. It helps optimize the skin's atmosphere to promote the natural production of hyaluronic acid and collagen, visibly improving skin elasticity for visible renewal. After one week of use, expect smoother, healthier, stronger, and younger-looking skin with more vibrancy and resilience. After 60 days of consistent use, skin is visibly more resilient and replenished, and looks stronger than ever.

Day 01

Day 30

BARRIER in the Press

“It’s literal beauty sleep in a bottle.”


"It has transformed my lackluster post-winter skin into a plumper, glowier situation, making it worth every penny.”

Who What Wear

“This cream is like a moist hug (sounds gross, but trust me) for my parched skin that instantly hydrates and calms my face. It melts in, leaving me with a cushiony complexion.”


"If you’re plagued with chronically dehydrated skin, your parched complexion has met its match in this concentrated overnight treatment from U Beauty."


"The BARRIER targets skin's stem cells to spur the proliferation of new cells. The payoff: a 22% increase in skin-barrier integrity after a single application."

Vanity Fair

"I go to bed juicy and plump, I wake up exactly the same."

She Knows

Skin by You. Routine by U Beauty.

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Leaping Bunny + Positive Luxury Certified

Manufactured with 100% green energy in a Co2-free facility.
Made in Italy

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Additional Information

U Beauty's BARRIER Bioactive Treatment is our skin-renewing night cream that promotes softer, more resilient skin. Our SIREN Capsule Technology’s IMMORTAL-SIREN works with our SIREN Capsule Technology promotes new growth and improves skin barrier integrity. Bioactive marine ingredients target damaged areas for ultimate skin radiance, while being gentle enough for sensitive skin. This overnight skin-renewal cream is infused with Shea Butter, Hyaluronic Acid, Purified Oat Extract, and Fruit Hydroxy Acids to protect from water loss and improve skin tone. Jojoba, Sunflower, and Mimosa Waxes promote optimal moisture levels and skin elasticity. Vitamin B6 promotes healthy oil production and improves skin texture, while Sodium DNA improves the appearance of fine lines and wrinkles to deliver fast results and healthy skin. Whether you have oily skin, combination, or dry skin, this calming night cream will deliver visible enhancements for reborn skin. Visibly enhance your skin by pairing The BARRIER Bioactive Treatment with our brightening serum, the Resurfacing Compound, with results emerging in just 3-6 days of use and our luxury moisturizer, The SUPER Hydrator, delivering mega-dose of hydration for up to 48 hours.