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±Catalano A, Mitri K, Perugini P, Condrò G, Sands C. J Cosmet Dermatol. 2023;22:3329–3339. doi:10.1111/jocd.16016. Note: Study authors include the patent inventors and patent owner representative.
*Based on an independent in vitro study using oxidative stress-treated human keratinocyte cells (HaCaT), comparing ROS production in SIREN-treated cells (5 mg/mL) versus placebo-treated cells. Results showed statistically significant inhibition of menadione-induced ROS release (p<0.01).
**Based on an independent instrumented study (CM 825 Corneometer; Tewameter TM 300) with 30 healthy female participants aged 36–58, comparing net effect of SIREN-treated skin versus placebo after 4 weeks of daily application.
***Based on an independent in vivo topographical 3D analysis (dermaTOP/Breuckmann OPTOCAT) with 30 participants, measuring percent variation from baseline after 28 days of daily application.
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U Beauty is a skincare innovation that honors your moment with fewer, better products designed to transform your skin and give you time back. Our formulas are rigorously tested, clinically validated, and multitasking by design—and all powered by multi-patent-pending SIREN Capsule Technology™, a precision delivery system that adapts to your unique concerns as they evolve throughout your life.
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