The Day-to-Night Duo

$311

(

$366 value

)

The Day-to-Night Duo

$311

( $366 value )

The Barrier is a highly concentrated, restorative overnight treatment that uses bioactive marine ingredients to optimize normal skin renewal to deliver visibly softer, stronger skin with improved-looking vibrancy and resilience.

Multimodal Defender Broad Spectrum SPF 30 is a next-generation treatment that helps visibly reduce hyperpigmentation, dark spots, heat-induced freckles, and fine lines while offering broad spectrum protection against UVA, UVB, and blue light rays, as well as the drying effects of the sun.​

1 - Barrier Bioactive Treatment 50ml
1 - Multimodal Defender 50ml


Made in Italy

$311
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60-DAY RETURN PROMISE

Subscriptions are not eligible for additional discounts.

The Day-to-Night Duo
The Day-to-Night Duo - ( x )

Key Concerns + Benefits

Improved Barrier Function

Boost Skin Renewal

Hyperpigmentation + Dark Spots

Epidermal Photoprotection

up to

+159%

Increase in collagen expression

up to

+148%

Increase in elastin expression

up to

-40%

Reduction in dark spots

up to

+78%

Prevention in skin temperature increase

How It Works

SIREN Capsule Technology

A proprietary ingredient delivery system that utilizes free radicals for targeted benefits: SIREN Capsules activate where the visible effects of free radicals accumulate—while avoiding the exposure of harsh ingredients to areas that don't need treatment, cleverly avoiding associated side effects, like dryness and irritation.

Each SIREN Capsule is packed with a strategic blend of antioxidants, hyaluronic acids, peptides, probiotics, and more to address the skin's unique needs for transformative-looking results.

Key Ingredients

Urea

A keratolytic with both hydrating and exfoliating properties that significantly improves skin elasticity.

Vitamin C

Promotes normal cell turnover, calms skin appearance, and optimizes collagen synthesis.

Vitamin B6

Promotes healthy oil production, while helping ameliorate rough skin and inflammation.

Zinc Oxide

FDA-approved broad-spectrum mineral filter reduces redness and free radical aggressors, and protects skin from UVA, UVB, blue light, and heat exposure.

Sodium DNA

A functional bioactive that has been clinically demonstrated to minimize the appearance of wrinkles and age-related wear on the skin.

Hyaluronic Acid, Vitamin E, Shea Butter, Jojoba and Almond Oils

Defend, nourish, plump, and smooth the skin's appearance.

Salicylic Acid

Supercharges the skin’s ability to shed dead cells from its top-most layer.

Urea

A keratolytic with both hydrating and exfoliating properties that significantly improves skin elasticity.

Vitamin C

Promotes normal cell turnover, calms skin appearance, and optimizes collagen synthesis.

Vitamin B6

Promotes healthy oil production, while helping ameliorate rough skin and inflammation.

Zinc Oxide

FDA-approved broad-spectrum mineral filter reduces redness and free radical aggressors, and protects skin from UVA, UVB, blue light, and heat exposure.

Sodium DNA

A functional bioactive that has been clinically demonstrated to minimize the appearance of wrinkles and age-related wear on the skin.

Hyaluronic Acid, Vitamin E, Shea Butter, Jojoba and Almond Oils

Defend, nourish, plump, and smooth the skin's appearance.

Salicylic Acid

Supercharges the skin’s ability to shed dead cells from its top-most layer.

View Complete List of Ingredients

Sustainable Packaging

LEAPING BUNNY CERTIFIED  |  Learn more

Few skincare products follow through on their promises, but this actually lives up to the hype.

— InStyle
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The Day-to-Night Duo
  • The RETURN Eye Concentrate
  • Resurfacing Compound
  • The PLASMA Lip Compound
  • The U Beauty Duo
  • The SUPER Hydrator
  • The BARRIER Bioactive Treatment
  • The SCULPT Arm Compound
  • Multimodal Defender Broad Spectrum SPF 30
  • The SUPER Body Hydrator
  • The MANTLE Skin Conditioning Wash
  • The SUPER Duo
  • The Brightening Duo
  • The Preface Set
  • The Index Set
  • The Brush
  • The Winter Set
  • The Resurfacing Set
  • The Body Set
  • The Index Set Vol. II
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  • Highest Rating
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  • 20-29
  • 30-39
  • 40-49
  • 50+
  • All
  • Normal
  • Oily
  • Dry
  • Combination
  • Sensitive
  • Aging Skin
  • Uneven Skin
  • Dark Spots
  • Blemishes
  • Fine Lines/Wrinkles
  • Sun Damage

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